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I don't see you mentioning gravity. Early human development, even in the womb, relies quite a bit on gravity. I'm not sure that human children would develop normally in the 0.4g gravity of Mars. Healthy adult astronauts have significant health issues after a long stay in the ISS, even with all the exercise they do to retain muscle mass. So I guess even if we could terraform Mars by overcoming the hurdles mentioned in this article, I'm not sure a permanent human civilization could survive without some sort of artificial gravity.

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